Objective To establish scrap indicators for key equipment in blood screening laboratory of blood centers and quantitatively assess the running status of key equipment, so as to provide a scientific method for equipment scrap.Methods Through the literature review and Delphi method, the scrap indicators of key equipment in blood screening laboratorie
Integration of therapeutic cargo into the human genome with programmable type V-K CAST
Abstract CRISPR-associated (Cas) transposases (CAST) are RNA-guided systems capable of programmable integration of large segments of DNA without creating double-strand breaks.Engineered Cascade CAST function in human cells but are challenging to deploy due to the complexity of the targeting components.Unlike Cascade, which require three Cas protein
Construction of Patent Claims Using Axiomatic Design
Patent claims play an important role in every patent case Socks and it is the core for evaluation of infringement, validity or originality.There are two main types of claims: the independent claims (stand on their own), and the dependent claims (depending on a single/several claim/claims).Axiomatic design is a design theory that is based on the axi
Comparative Analysis of the Degree of Food Security Assurance at Global Level
people with security and safety, namely to protect and maintain the rights KYOTO RED MISO of its citizens and to provide them with an environment conducive to the satisfaction of all their needs.Among the dimensions of national and international (collective) security, food security and safety represent the most important dimension of the internal s
Connectome-based biophysical models of pathological protein spreading in neurodegenerative diseases.
Neurodegenerative diseases are a group of disorders characterized by progressive degeneration or death of neurons.The complexity WOMAN BLACK COHOSH of clinical symptoms and irreversibility of disease progression significantly affects individual lives, leading to premature mortality.The prevalence of neurodegenerative diseases keeps increasing, yet